Having genital herpes could increase the risk of being infected with HIV, the virus which causes AIDS, and it can lead to serious problems for people living with HIV.
The person who have genital herpes sores are more likely to be infected with HIV during the intercourse. When you develop a sore, your immune system will try to heal it, so there are many immune cells concentrated in that spot of sore. Those are the cells that HIV infects.

The Compound Effect of Genital Herpes and HIV

Both HIV and the herpes virus are troubles, as one can bring side effect to the other. Research shows that it might cause HIV to make replication than it will otherwise, when the herpes virus is active. More and more HIV replicates, the body’s infection-fighting cells it destroys by inches, eventually leading to AIDS.
People infected with both HIV and the herpes virus might have longer-lasting, more frequent, and more severe outbreaks of herpes symptoms, because a weakened immune system can’t keep the herpes virus under control as well as a healthy immune system can.

Treatment Issues for HIV and Genital Herpes

When you also have HIV, it becomes more difficult to treat genital herpes. Higher doses of antiviral drugs are often needed to treat herpes in people with HIV. If you have HIV, ask your doctor if you shall be tested for genital herpes. If you already know that you have herpes and HIV, please do discuss treatment options with your doctor. Many people with HIV have strains of the herpes virus which are resistant to treatment with the standard antiviral drugs.
If you have taken antiviral drugs for genital herpes and the treatment did not work, your doctor can consider testing the virus you have for resistance. If the virus is resistant, there are other possible alternative treatment, including the drugs Foscavir and Vistide. These drugs can be given through an IV, or a Visited gel can be applied to the herpes sores.